The constipation is REAL though. Like 10 plus days real. That scare story might be extreme but severe constipation is pretty common (and fecal vomiting can be a result of extreme constipation/impaction I believe)
If you don't have a regime that supports the medication, you could suffer some real problems. Drinking a LOT of water is mandatory. As well as eating lots of fiber - like good p-fruits (plum/pear/peach/etc) or benefiber/laxative.
I've had no problems following the advice of my weight loss program and r/Zepbound etc.
Some forms of magnesium trigger more stool my movement than others. And there are many forms.
I had opposite problem with it, tried ti find what won't cause it since I have a problem with it too behind with. Also sour kraut triggers me almost always and instant toilet break.
You mentioned elsewhere that milk of magnesia worked, so is it possible that you received a bunk product? I know this is a common issue with supplements and there are some neutral third-party test labs for this.
For what it's worth, GLP-1s helped significantly with my IBS-D, and current research shows they're more effective and better tolerated than bile acid sequestrants.
Ultimately you get these extreme issues if you ignore a problem for too long. If you are becoming constipated and let it continue for many days on end without seeking some kind of treatment I feel that you are kinda to blame. I had some constipations at one point while on it and used some over the counter style fiber products and stool softeners to deal with the problem. If I ignored the problem of course I could potentially end up in these more extreme situations.
I think if people are choosing to use such medications they should make sure they are aware of the potential complications and are vigilant with their health to ensure these extreme side effects are avoided.
Fibre and stool softeners did nothing for me. Nor increasing water. Nor exercise. Nor massaging my stomach. Nor senna
Only a magnesium drink ("Milk of Magnesia") or bisocodyl, neither of which are pleasant to take regularly as they result only in diarrhoea
It's hard to balance trying to let your body do its thing with less extreme method and resorting to the nuclear option. You also have to write off a day and not go anywhere after taking those
It's very much related to the drug and not just "ignoring" something
I only had an issue because I was taking an iron supplement at the same time which also can further cause constipation. I stopped taking that and it resolved my constipation issues.
I'm not too sure what you're referring to with a "write off day". I am on the highest dose currently and don't have this issue. I maybe get some sleepiness the day after taking it but I can still do things. However that effect has also subsided a lot after taking it for long over.
Every medication will have pros and cons. I'm having huge success on the medication and the slight issues I have are a worthy tradeoff personally.
Oh wow that sounds like the opposite issue! I've only had the other problem where it's not coming out. It's funny how medications can cause issues where they constipate people, but then also have the opposite problem where they make people have diahrea.
Yes (not that exact brand but the same ingredient: polyethylene glycol 3350). It takes 3-5 days to begin working then creates diarrhoea for another 3-5 days
(I probably should mention I had IBS-C prior but Mounjaro makes it 2-3x worse)
