VB6 could make apps that adapted themselves to window size, which was more flexible than different screen sizes.

It was no Apple's Cassowary, but so isn't HTML/CSS.

Some of the Wordpress, Drupal and Squarespace theme designers do the drag/drop GUI part where you can drop into the html, but it's more for graphic designers than programmers. I have watched a graphic designer be super productive with the WP Divi theme builder. But graphic designers are used to Adobe-like products with visual designers.

Yet things that were built, have been used.

Unfortunately the days of assuming everyone has a mouse, keyboard, and at least 4”x6” of screen to place a window on are long gone.

And yet apparently they've never been good enough, because people keep asking for it.