Agreed, and also it's worth noting that we're talking about companies here. Yes, for any individual the amount of money lost is insane, but that's the risk for the company. If one individual can accidentally nearly bankrupt the company, then the company did not have proper risk management in place.
That isn't too say that it wouldn't also affect my sleep quality.
Depending on the company's culture, that calculus can vary. If management start firing subordinates for making mistakes, then what should be done to management if they fail to account for human error, resulting in multimillion-dollar losses?
That isn't too say that it wouldn't also affect my sleep quality.