My hometown did this in the late 90's, added three barriers across intersections to cut a neighborhood in half. Here's someone recently suggesting removing them to alleviate traffic on the main north/south road (under construction for the last two years or so), but I doubt anything would happen to them:
Traffic bound for North Atherton (bottom left of map) has to go down to the intersection with Park instead of taking Allen.
Easy enough to take a bike through them, I used to ride that way regularly in to campus. But I think it's worked well to not have cars shortcutting through the neighborhood at high speeds.
On the street near me there are just chikanes every 100 metres or so, that massively discourages people from using it for using it as a shortcut, because at rush hours the chikanes become a massive pain in the ass:
But physically making the street not be a through street is possible. Just plop down a couple of Jersey walls and you're done.
Check out how Vancouver made semlin, grant, and gravely forcibly "no thru traffic" here: https://maps.app.goo.gl/DFVJNDF2DftbFzpv9