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This is TFUS [1] with a novel target.

It looks like independent hackers with a strong technical background and little regard for decorum.

Their methodology seems reasonable, and their results are plausible.

I’m reserved about the final part of the post where they moot about applications, but the core result seems solid. They elicited osmosphenes like one can elicit phosphènes by targeting the visual cortex.

1. https://en.wikipedia.org/wiki/Transcranial_focused_ultrasoun...


> Keeping in mind where the team are coming from [...]

Oh... could you elaborate?


I don't know the exact details, but as far as I remember they are a employees owned collective with social improvement goals, working on open source, and they are involved in the Orca screen reader for Linux.

Wikipedia and their about page give some more info, but they definitely have accessibility experience and the history of delivering stuff.


Great, thanks!


This is probably negligible, but the hammer is not perfectly rigid. The tension in the stem at the time the hammer escapes and subsequent oscillations could also play a role.


That's a fair point, but I don't think that would make a split between timbre and amplitude.


This little morsel was coagulating in my mind as I was reading all of these comments. No idea what, if any, effect there would be, but it is a variable.


And the best way to build trust in the new tool is naturally to sabotage the old one.

rv builds on André's reputation. The best way to squander it would be to attack the rubygem infrastructure.


You could also use a random salt (for i64, add it up with wrap around overflow) with minimal overhead.


The old, bug-ridden native XSLT code could also be shipped as WASM along with the browser rather than being deprecated. The sandbox would nullify the exploits, and avoid breaking old sites.

They actually thought about it, and decided not to do it :-/


I don't know if the evidence is more than anecdotal, but I've read that ADHD smokers who are taking adderal have to increase the dose of their treatment to remain functional when they quit smoking.

I've been taking nicotine patches for half a year now, with great success (and it is available OTC unlike other stimulants). Nicotine in itself isn't toxic at these doses (7, 14, 21mg), it's a cool life hack :-).


I enjoy cigars and notice the positive effect, my fear with the patches or Lucy/zyn is that it not being self limiting seems to lead to people having one in their lip literally every waking minute when they’re not eating.


Patches are changed once per day, and their pharmacokinetics isn't addictive (the nicotine blood levels rise too slowly to give you a dopamine boost).

I sometimes realize in the afternoon that I forgot to change my patch in the morning because I'm a bit drowsy (a feeling not unlike being uncaffeinated when you're used to drinking coffee). AFAIK the withdrawal symptoms fade out in at most a week.


I tried vibe coding WebGPU/WGSl, which is thoroughly documented, but has little actual code around, and LLMs are pretty bad at it right now.

They don't need a formal model, they need examples from which they can pilfer.


I've had a similar problem with WebGPU and WGSL. LLMs create buffers with the wrong flags (and other API usage errors), doesn't clean up resources, mix up GLSL and WGSL, write semi-less WGSL (in template strings) if you ask them to write semi-less [0] JS...

It's a big mess.

0. https://github.com/isaacs/semicolons/blob/main/semicolons.js


TMAO is the precursor of imidazole propionate.


No, it is not. imidazole propionate is made by gut bacteria metabolizing histidine.

https://www.caymanchem.com/product/33458/imidazole-propionat...


My bad, I read the paper too fast.


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